Tricalcium phosphate = TCP

CAS Number: 7758-87-4
EC Number: 231-840-8
Linear Formula: Ca3(PO4)2
Chemical formula: Ca3(PO4)2
Molar mass: 310.18
E number: E341

Tricalcium Phosphate is used as an anti-caking agent in dry vinegar and salts.
Tricalcium Phosphate’s also used as a calcium source for cereals.
Due to its white color, Tricalcium Phosphate can also be used to bleach flour and to improve coloring.
Tricalcium phosphate is a supplement form of calcium phosphate and is used to treat or prevent calcium deficiency.
Calcium is primarily important for healthy bones and teeth.
Calcium is naturally found in foods like dairy, nuts and seeds, and dark, leafy vegetables.
In addition to Tricalcium Phosphates use as a supplement, tricalcium phosphate is used as an anti-caking agent in powdered food items.
Tricalcium Phosphate is also used as an additive in some processed foods to boost calcium content.

Tricalcium phosphate is a calcium salt found in many nutritional supplements.
Many people wonder about the safety of tricalcium phosphate, including side effects and whether Tricalcium Phosphate causes cancer.
Tricalcium phosphate (sometimes abbreviated TCP) is a calcium salt of phosphoric acid with the chemical formula Ca3(PO4)2.
Tricalcium Phosphate is also known as tribasic calcium phosphate and bone phosphate of lime (BPL).
Tricalcium Phosphate is a white solid of low solubility.
Most commercial samples of “tricalcium phosphate” are in fact hydroxyapatite.
Tricalcium Phosphate exists as three crystalline polymorphs α, α’, and β. The α and α’ states are stable at high temperatures.

What Is Tricalcium Phosphate?
Calcium Phosphate, Dicalcium Phosphate, Dicalcium Phosphate Dihydrate and Tricalcium Phosphate are all calcium salts of phosphoric acid.
Calcium, Dicalcium and Tricalcium Phosphate are also known as monobasic, dibasic and tribasic Calcium Phosphate, respectively.
When two water molecules are bound to Dicalcium Phosphate Tricalcium Phosphate is called Dicalcium Phosphate Dihydrate.
In cosmetics and personal care products, the Calcium Phosphate ingredients are used in the formulation of blushers, dentifrices, eye makeup, eyeliners, face powders, foundations, lipsticks, other makeup products and skin care products.

Why is Tricalcium Phosphate used in cosmetics and personal care products?
The following functions have been reported for the Calcium Phosphate ingredients.
Abrasive – Calcium Phosphate, Dicalcium Phosphate, Dicalcium Phosphate Dihydrate, Tricalcium Phosphate
Buffering agent – Calcium Phosphate
Bulking agent – Calcium Phosphate
Opacifying agent – Dicalcium Phosphate, Dicalcium Phosphate Dihydrate, Tricalcium Phosphate
Oral care agent – Calcium Phosphate, Dicalcium Phosphate, Dicalcium Phosphate Dihydrate, Tricalcium Phosphate

Scientific Facts about Tricalcium Phosphate:
Calcium Phosphate is often used as a dietary supplement in prepared breakfast cereals, enriched flour and noodle products.

The use of calcium (Ca) supplements by postmenopausal women is growing rapidly.
A commercial preparation of tricalcium phosphate (TCP) is available in the USA.
Depending on the relative absorption of Ca versus phosphate, a rise in serum phosphorus (P) could stimulate parathyroid hormone (iPTH) secretion.
We therefore compared Ca absorption and the metabolic responses following TCP to that of Ca carbonate (CC) on separate occasions in each of 10 women, aged 22-40 years.
The subjects were fasted overnight for 12 hours while good hydration was maintained.
Following a 2-hour baseline-urine collection, 1200 mg calcium (as CC or TCP) was ingested and two 2-hour postload urine collections were made.
Blood was drawn at 1, 2, and 4 hours after the Ca load.
Serum (S) and urine (U) Ca, P, and creatinine, and U cyclic AMP (cAMP) were determined. iPTH levels following TCP were also measured.
Ca absorption was determined by the postload rise in Uca above baseline.
Uca excretion increased significantly and was accompanied by significant rises in Sca after both preparations.
Following TCP, S and U phosphorus increased. Urinary cAMP did not change after either preparation, and iPTH levels fell after oral TCP.
We conclude that Ca taken as TCP is absorbed adequately and, thus, despite a rise in the S phosphorus level does not stimulate parathyroid activity.

Important Facts About Tricalcium Phosphate:
-Chemically, tricalcium phosphate is a calcium salt of phosphoric acid.
-Tricalcium Phosphates primary function in fortification is to increase the calcium content of foods.
-Tricalcium Phosphate is almost insoluble in water, has a very low flavor profile and usually comes in a fine white powder.
-The chalky texture of tri-calcium phosphate makes Tricalcium Phosphate useful as a free-flowing agent, as Tricalcium Phosphate has the ability to take up to 10% of Tricalcium Phosphates weight in moisture.
-Tricalcium Phosphates texture and color properties also make Tricalcium Phosphate an effective clouding agent.
-Tricalcium phosphate’s E-number is E341(iii), a subclass of calcium phosphates for those who may need to check the additive status for their country.
-Tricalcium Phosphate has a CAS Number of 7758-87-4.
-Ingredient labels list Tricalcium Phosphate as tribasic calcium phosphate, tri-calcium orthophosphate, and precipitated calcium phosphate, or Tricalcium Phosphate’s labeled in formulation paperwork as TCP.
-Due to its mineral source, Tricalcium Phosphate can be used in vegan foods and is also allowed in organic products in the US.

Tricalcium Phosphate Health Benefits
Calcium is stored primarily in the body’s bones and teeth.
Calcium is important in children and adolescents who require it for bone growth and development.
Adults also need calcium to maintain strong, healthy bones and teeth.
Calcium is most readily absorbed through foods that are naturally high in calcium.
Sometimes people who have lactose intolerance or who are vegan may not get enough calcium through their diets.

Examples of how tricalcium phosphate functions in food manufacturing:
-Acidity regulator
-Adds smoothness and opacity to reduced fat foods and beverages, such as soymilk
-Anticaking agent
-Calcium and phosphorus mineral fortification– seen in some juices, soy beverages, and cereal products
-Clouding Agent
-Firming agent – interacts with gelling agents to strengthen a food structure
-Flour Treatment Agent
-Humectant in some table salts, sugar, or baking powder
-Stabilizer in some fats for frying
-Leavening agent in some baked goods & breadings
-Mineral salt in cheese products

Tricalcium phosphate is a calcium salt of phosphoric acid.
Tricalcium Phosphate is a white solid of low solubility.
Tricalcium phosphate’s E-number is E341(iii).
Tricalcium Phosphate is naturally found in cow’s milk.

Tricalcium Phosphate Health benefits
Tricalcium phosphate contains both calcium and phosphorus, both of them are important minerals for bone health.
Tricalcium phosphate also contain Vitamin D, which helps you to absorb the calcium and phosphorus much more easily.

What are the Uses of TCP?
Tricalcium phosphate is an ingredient used in many applications.
Tricalcium Phosphates food grade is commonly used as an anticaking agent to make powdered food free-flowing, also as a nutritional supplement supplies both calcium and phosphorus minerals in fortified foods.
Meanwhile, Tricalcium Phosphate can be used as a whitening color to replace titanium dioxide.
Other applications like in baby powder, toothpaste, and pharmaceuticals.

Tricalcium Phosphate in Food
Anticaking agent
Tricalcium phosphate is used to prevent powdered food from caking, lumping, or aggregation and improve the fluidity.
We can commonly find Tricalcium Phosphate in powdered drink, powdered milk, non dairy creamer, instant powders, table salt, spices and etc.

Tricalcium Phosphate and Nutritional supplement
Tricalcium phosphate is a source of calcium and phosphorus.
Tricalcium Phosphates main function in food fortification is to increase the calcium supplement due to its higher calcium content.
The applications such as in cereals, dairy products (e.g. yogurt), juices, multivitamins and pharmaceuticals.
Tricalcium Phosphates calcium content is higher than that of monocalcium phosphate, which is used as a leavening acid in baking powder.
Our absorption of calcium would be more efficient when combined with vitamin D.
Calcium carbonate and calcium citrate are two common calcium supplements.

Tricalcium phosphate (sometimes abbreviated TCP) is a calcium salt of phosphoric acid with the chemical formula Ca3(PO4)2.
Tricalcium Phosphate is also known as tribasic calcium phosphate and bone phosphate of lime (BPL).
Calcium phosphate is one of the main combustion products of bone (see bone ash).
Calcium phosphate is also commonly derived from inorganic sources such as mineral rock.
Tricalcium phosphate is used in powdered spices as an anticaking agent.
Tricalcium Phosphate is also found in baby powder.
Calcium phosphate is also a raising agent (food additive) E341.
As a mineral salt found in rocks and bones, it is used in cheese products.
Tricalcium Phosphate is also used as a nutritional supplement and occurs naturally in cow milk, although the most common and economical forms for supplementation are calcium carbonate (which should be taken with food) and calcium citrate (which can be taken without food).
Calcium triphosphate is used to remove fluoride from water in water filtration systems.

Tricalcium Phosphate and Feed
TCP can also be a dietary supplement of calcium and phosphorus in pet food, e.g. in cat and dog food.
Tricalcium Phosphate benefits cat and dog in building bones, nerve impulse transmission and other benefits.

Tricalcium Phosphate in Cosmetics
Per “European Commission database for information on cosmetic substances and ingredients”, Tricalcium Phosphate functions as an abrasive, anticaking, masking, opacifying amd oral care agent in cosmetic and personal care products.

Tricalcium Phosphate in Toothpaste
Calcium and fluoride will join together to form calcium fluoride in toothpaste, which makes the fluoride less effective in preventing tooth decay.
Functionalized tricalcium phosphate produced by beta-tricalcium phosphate and sodium lauryl sulfate can prevent this reaction during the storage of toothpaste and thus generate more fluoride and calcium ions to remineralize enamel and protect the dental from caries.

Is Tricalcium Phosphate Safe to eat?
Yes, Tricalcium Phosphates safety when used as a food additive has been approved by the U.S. Food and Drug Administration (FDA), European Food Safety Authority (EFSA),  Joint FAO/WHO Expert Committee on Food Additives (JECFA), as well as other authorities.

Some calcium phosphates derive from phosphate rocks, calcium from plant sources, and ammonia.
These can be considered vegan.
Most of the time, however, calcium phosphates are made from ground animal bones.
Calcium phosphate aids in cell functioning and plays a vital role in many different body processes, including bone growth and energy production.
Tricalcium phosphate is effective as a nutritional supplement because it is readily absorbed in the body.
However, there is little evidence to show Tricalcium Phosphate is more effective than other calcium supplements, in particular, those containing citrate and carbonateTrusted Source.
Tricalcium phosphate also has many other uses.
Tricalcium Phosphate is found in many household items, including baby powder, toothpaste, and antacids.
A variety of industries use tricalcium phosphate.
For example, the biomedical sector uses tricalcium phosphate to make cement or composite to repair bones.

Tricalcium phosphate is a calcium salt of phosphoric acid that is commonly used as an ingredient in food products and nutritional supplements.
Tricalcium Phosphate also sees use in a wide range of other products from toothpaste and antacids to water filtration systems and bone grafting material.
Tricalcium phosphate typically comes in a fine white powder that is almost insoluble in water.
Tricalcium Phosphates chalky texture makes Tricalcium Phosphate useful as a free-flowing agent.
Due to its white color, Tricalcium Phosphate can also be used to bleach flour and to improve coloring.
And due to its mineral source, tricalcium phosphate can be used in vegan foods and is also allowed in certified organic products in the US.

IUPAC name
Tricalcium bis(phosphate)
Other names
Tribasic calcium phosphate

Tricalcium Phosphate (sometimes abbreviated TCP) is a calcium salt of phosphoric acid with the chemical formula Ca3(PO4)2.
Tricalcium Phosphate is also known as tribasic calcium phosphate and bone phosphate of lime (BPL).
Tricalcium Phosphate is a white solid of low solubility.
Most commercial samples of “tricalcium phosphate” are in fact hydroxyapatite.

Tricalcium phosphate is an ingredient that is heavily used across many industries – toothpaste, antacids, bone grafting material, baby powder, water filtration, nutritional supplements and ceramic coatings – and it is also in our food supply.
Tricalcium phosphate (EU) is a mineral found in many foods, for many purposes.

Tricalcium Phosphate (TCP) is used as an anti-caking agent in dry vinegar and salts.
Tricalcium Phosphate is often used as an additive for milk powder, pudding and various types of flavoring.
Tricalcium Phosphate’s also used as a calcium source for cereals and is a nutrition enhancer.
This ingredient can be used in foods such as dairy products, wine, carbonated beverages, candy and jams.
Tricalcium Phosphate can also be used in some liquid foods to add smoothness and an opaque color.
Tricalcium Phosphate can be added to food for strengthening calcium intake, and is sometimes used to prevent or treat the symptoms of lack of calcium.
Due to its white color, Tricalcium Phosphate can also be used to bleach flour and to improve coloring.
Tricalcium phosphate is sometimes added to calcium supplements.
Tricalcium phosphate is a white, odorless and tasteless.
Tricalcium Phosphate should be stored in a dry and ventilated area and should be kept away from water and moisture.

Various calcium phosphates are used for bone repair.
Although hydroxyapatite (HA) sintered ceramics are widely used due to their osteoconductivity, Tricalcium Phosphates bioresorbability is so low that HA remains in the body for a long time after implantation.
In contrast, tricalcium phosphate (TCP) ceramics show resorbable characters during bone regeneration, and can be completely substituted for the bone tissue after stimulation of bone formation.
Therefore, much attention is paid to TCP ceramics for scaffold materials for supporting bone regeneration.
This paper reviews bioresorbable properties of calcium phosphate ceramics derived from β-TCP and α-TCP.

CAS Number: 7758-87-4
CHEBI: 9679
ChemSpider: 22864
ECHA InfoCard: 100.028.946
PubChem CID: 516943
UNII: K4C08XP666 check
CompTox Dashboard (EPA): DTXSID1049803

Properties of tricalcium phosphate and effects of many other ingredients upon the structure and solubility of the phosphate were investigated.
By the reaction of calcium salts with phosphates in aqueous solution, tricalcium phosphate hydrate with a definite structure is not formed but hydroxy apatite with an excess of phosphoric acid is formed, which varies to β-tricalcium phosphate by heating between 700–800°C.
Contrary to many other reports, it was found that β-tricalcium phosphate was fairly soluble in citric acid.
The solubility is reduced remarkably by a small amount of admixtures, especially of magnesia.
Magnesia stabilizes the β modification and prevents β→α inversion of the phosphate.
The effect of alumina and ferric oxide is similar but not so intense as magnesia.
On the contrary, barium oxide stabilizes the α modification.
Sodium oxide affects variously according to the ratio of substitution for lime.
Constitution and solubility of phosphate fertilizers were discussed in relation to these results.

Tricalcium Phosphate or TCP can be used as a calcium and/or phosphorus nutrient supplement in pharmaceuticals and multivitamins.
Certificate of suitability No. R1-CEP 2006-255-Rev 00 has been granted for the sale of this product in Europe as a pharmaceutical grade ingredient.
A copy of the certificate is available upon request.
TCP can be used as an excipient in the preparation of tablets for pharmaceutical or over-the-counter (e.g., multivitamin) products.
TCP can be used as a desensitizer in certain toothpaste formulations.
Potable Water Treatment: ICL Performance Products LP tricalcium phosphate conforms to the requirements of ANSI/NSF Standard 60; used for purposes of defluoridation.
Maximum Use Level = 120 mg/L.

Signs of calcium deficiency may include:
-Muscle cramps and spasms
-Tingling in the hands and feet
-Memory difficulty
-Brittle nails and bones
In post-menopausal people, when bone-breakdown occurs faster than new bone is generated, adequate calcium is especially important in preventing osteoporosis

Tricalcium phosphate (Ca3(PO4)2) is a calcium salt of phosphoric acid.
Containing both calcium and phosphoric acid gives tricalcium phosphate many positive health and pharmaceutical benefits as well as industrial uses.
Below are only a few of the many uses of this marvelous product stocked by Bell Chem, your Florida chemical supplier.

Cheesemaking and other industries employ tricalcium phosphate to regulate acidity.
Baked goods often list tricalcium phosphate as an ingredient.
When bread is baked, tricalcium phosphate causes bread to rise properly.
Reduced fat liquids containing tricalcium phosphate are generally smoother and thicker.
Many spices contain tricalcium phosphate because Tricalcium Phosphate deters caking and clumping.
As a matter of fact, from baby powder and agricultural applications, thousands of products take advantage of tricalcium phosphate’s anti-caking properties.
When pharmaceuticals need to be routed directly to osseous tissue (bone), tricalcium phosphate acts as a delivery system, bringing the medication directly to the bone.

In antacids, the basic properties of tricalcium phosphate act to buffer the acid environment of the stomach while supplying the body with calcium, an important component of every body system.
Common medical practice utilizes tricalcium phosphate as a supplement or stand-alone bone graft agent.
Home water filtration systems find tricalcium phosphate works well to remove fluoride from water.
Fertilizers often contain large amounts of phosphoric acid, which is typically derived from tricalcium phosphate.
Your body cannot function without calcium or phosphate.
Calcium is imperative for muscle contraction, heart rate regularity, and, Tricalcium Phosphates most well-known function, bone health.
Phosphate is less well recognized but is essential in the formation of cellular membranes, nucleic acids (DNA and RNA), energy production within cells, and bone mineralization (hardening).
Supplementing your diet with tricalcium phosphate will ensure you receive the correct amounts of both nutrients daily.

Some people take supplements containing tricalcium phosphate to supplement their daily calcium intake if they are not getting enough calcium from diet alone.
However, tricalcium phosphate is a concentrated source of calcium and taking too much can cause high calcium levels or hypercalcemia.

Food additive
Tricalcium phosphate is used in powdered spices as an anticaking agent, e.g. to prevent table salt from caking.
The calcium phosphates have been assigned European food additive number E341.

What is Tricalcium Phosphate?
TCP is a subclass of calcium phosphates and makes up of a variable mixture of calcium phosphates and having the approximate composition of 10CaO·3P2O5 ·H2O.
Tricalcium Phosphate can be used in vegan food and supplement for its mineral origin.

What is Tricalcium Phosphate Made From?
Food grade TCP can be produced by the reaction of phosphoric acid with calcium carbonate or calcium hydroxide OR the reaction between calcium chloride solution and trisodium phosphate.

Chemical formula: Ca3(PO4)2
Molar mass: 310.18
Appearance: White amorphous powder
Density: 3.14 g/cm3
Melting point: 1,670 °C (3,040 °F; 1,940 K)
Solubility in water: 1.2 mg/kg

Although caries continues to be the most prevalent dental disease worldwide, significant reductions in dental caries have been reported over the past 30 years.
The decline is attributed to nearly universal use of products containing fluoride, such as toothpastes and oral rinses, as well as professionally applied compounds containing higher concentrations of fluoride.
Fluoride is proven to prevent tooth decay.
Tricalcium Phosphate does so by inhibiting demineralization, enhancing remineralization, and inhibiting bacterial activity in dental plaque.
In recent years, we’ve advanced our understanding of the roles calcium and phosphate also play in remineralizing toothpastes and other dental products.
Clinical trials have shown that applying products with high concentrations of both calcium and fluoride may not result in greater protection against tooth decay.
That’s because the calcium and fluoride can combine during storage to form calcium fluoride—which renders the fluoride less effective in preventing tooth decay.
However, 3M ESPE has introduced a proprietary calcium phosphate ingredient, Tri-Calcium Phosphate (TCP), that can be protected from unwanted interactions with fluoride during storage.
This protected calcium additive works with fluoride to initiate high-quality mineral growth—acting as a catalyst to enhance remineralization and build a high-quality, acid-resistant mineral.
In addition, this innovative technology in toothpaste can be tailored to provide short- or long-term mineral delivery in a variety of dental products.

Tricalcium Phosphates Clinical Applications
Fluoride Toothpaste
As the functionalized TCP ingredient is protected from unwanted interactions with fluoride within the toothpaste during storage, Tricalcium Phosphate remains stable and allows for more fluoride availability.
During brushing, both fluoride and the TCP ingredient are delivered to the tooth and provide enhanced remineralization and added protection against demineralization.
Several laboratory studies have proven superior performance when the TCP material is added to fluoride toothpastes at optimal concentration.

Protects against lesion initiation and progression
The purpose of this study was to determine how well different toothpaste formulations protect against carious lesion formation and progression.
In this study, a well-established pH-cycling model was used to mimic enamel lesion initiation and progression.
Sound tooth enamel samples were subjected to periods of demineralization with an acid solution, and remineralization with various toothpaste treatments and artificial saliva.
Samples were analyzed using cross-sectional microhardness to ensure the entire lesion body was analyzed.

High levels of calcium can cause:
-stomach pain
-muscle pain
-excessive urination

Three years of inadvertent excessive inhalation and ingestion of the dust from a dentifrice resulted in the systemic accumulation of tricalcium phosphate crystals and granulomatous lesions in a patient who died from carcinomatosis apparently unrelated to the crystallosis.
Dyspnea and cough were the only symptoms.
Crystals detected in the tissues by high magnification and polarized light and identified by x-ray-diffraction analysis matched those of the dentifrice, and of standard tricalcium phosphate.
Continual heedless exposure to minute, insoluble, airborne crystals dispersed from widely used powdery abrasive substances may have caused other instances of systemic or pulmonic granulomas.

Application: Tricalcium phosphate is a calcium salt of phorphoric acid that has uses in fertilizers, as a food additive, water filtration, and in some medical applications.
Tricalcium Phosphate serves as a source of phosphorous for some fertilizers.
As a food additive, Tricalcium Phosphate is used as a raising agent or sometimes as a nutritional supplement.
Medically, Tricalcium Phosphate has application in bone graphs, but also as an antacid.

Compatibility: Tricalcium phosphate is incompatible with strong oxidizing agents, strong acids, and alkalis.
Please see SDS for full safety and compatibility information.

Why is calcium important?
Calcium is a nutrient that is essential for strong bones.
Ninety-nine percent of your body’s calcium is stored in your bones and teeth.
The other one percent of your body’s calcium is found in blood. Blood calcium is necessary to support your body’s critical functions such as controlling your blood pressure and maintaining your heartbeat.
The calcium in your bones makes up your bone bank.
Throughout your lifetime, the calcium from the foods you eat is “deposited” in and “withdrawn” from your bone bank, depending on your needs.
When your calcium intake is too low to keep your blood calcium normal your body will “withdraw” the calcium it needs from your bones.
Over time, if more calcium is taken out of your bones than is put in, the result may be thin, weak bones that may break more easily.

Consumers know calcium is important for bone and teeth health.
Cal-Sistent micronized Tricalcium Phosphate (TCP) from ICL Performance Products helps manufacturers provide calcium fortification without altering the well-established tastes or mouth feel of consumers’ favorite foods and beverages.
Produced through a unique manufacturing process, a minimum of 95 percent of Cal-Sistent’s TCP particles are less than 20 microns.
The small particle size makes Cal-Sistent ideal for products with a well-established taste or mouth feel because Tricalcium Phosphate is non-detectable in the human mouth, exhibits excellent suspension properties and does not affect product flavor.
Cal-Sistent delivers a calcium content of 38 percent and calcium to phosphorus ratios equivalent to those in human bones.
The calcium and phosphorus work synergistically to help prevent osteoporosis.

Also Known As
Other names include:
Tribasic calcium phosphate
Bone phosphate of lime
Calcium phosphate

Tricalcium phosphate [Wiki]
233-283-6 [EINECS]
7758-87-4 [RN]
Ca3(PO4)2 [Formula]
Calcigenol Simple [Trade name]
calcium diphosphate
calcium orthophosphate
calcium phosphate
Calcium phosphate (3:2) [ACD/IUPAC Name]
Calcium tertiary phosphate
Calciumphosphat (3:2) [German] [ACD/IUPAC Name]
Phosphate de calcium (2:3) [French] [ACD/IUPAC Name]
tertiary calcium phosphate
tribasic calcium phosphate

White shapeless powder; odorless; relative density: 3.18; hardly soluble in water but easily soluble in diluted Hydrochloric Acid and Nitric Acid; stable in air.
In food industry, Tricalcium Phosphate is used as anti-caking agent, nutritional supplement (calcium intensifier), PH regulator and buffer, e.g. to act as anti-caking agent in flour, additives in milk powder, candy, pudding, condiment, and meat; as auxiliary in refinery of animal oil and yeast food.

tri-Calcium (ortho)phosphate
tricalcium diphosphate
tricalcium orthophosphate
β-Calcium phosphate tribasic
β-Tricalcium phosphate
Calcium orthophosphate, tri-(tert)
Calcium Phosphate Nanoparticles
Calcium phosphate tribasic
Calcium phosphate, tribasic

A white amorphous powder also known as calcium orthophosphate or tertiary calcium phosphate or bone ash.
Tricalcium Phosphate is found naturally as a rock and also in the skeletons and teeth of vertebrate animals.
Uses: In powdered spices as an anti-caking agent, a raw material in the production of phosphoric acid and fertilizers, a raising agent, in cheese products, as a nutritional supplement, in porcelain and dental powders, as an antacide, and in gene transfection. CAS# (7758-87-4)

Tricalcium phosphate is a calcium salt of phosphoric acid with the chemical formula Ca3(PO4)2.

Other Names

Tricalcium bis(phosphate)
Tribasic calcium phosphate
Bone phosphate of lime

What Is Tribasic Calcium Phosphate?
Tricalcium phosphate (TCP), also known as tribasic calcium phosphate or E341, is a calcium salt of phosphoric acid produced through chemical synthesis.

Chemical formula

Uses of E341
Tricalcium Phosphate is used as a food additive with E number – E341.
According to the FDA, Tricalcium Phosphate is considered – GRAS (generally recognized as safe).
The daily limit of TCP is recommended to be 70mg.



EINECS 231-840-8
EINECS 233-283-6
EINECS 235-330-6
MFCD00867081 [MDL number]
Natural whitlockite
Phosphoric acid calcium(2+) salt (2:3)
Phosphoric acid, calcium salt (2:3)
Posture [Trade name]
Posture (TN)
tert-Calcium phosphate
tricalcium bis(orthophosphate)
tricalcium bis(phosphate)
tri-calcium phosphate
α-tri-Calcium phosphate
α-Tricalcium phosphate
β-tri-Calcium phosphate
磷酸钙 [Chinese]